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Chinese Drugmakers Scramble To Address Skyrocketing Demand For Ozempic

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These 7 Celebs Have Spoken Out About The Weight Loss Drug Ozempic


Chinese drugmakers are becoming more eager to grab a slice of the growing market for Ozempic in China amid the craze for the drug.

Though primarily used for treating diabetes, Ozempic has become a highly sought-after drug worldwide due to its purported weight loss effects. In China, where societal beauty standards prioritize extreme thinness, the frenzy surrounding Ozempic has led to shortages of the medication in the country.

Social Media Hype and Shortages

Chinese social media platforms, such as Douyin and Xiaohongshu, have been inundated with posts from users boasting about significant weight loss achieved with just a few injections of Ozempic (semaglutide). The posts, often accompanied by exaggerated claims, have fueled the drug’s popularity as a “wonder drug” for weight loss, according to CNN.

While Ozempic has been officially approved in China for the treatment of type 2 diabetes, medical experts cautioned against its use for weight loss. Studies and patient reports suggested that weight rebound is common once the injections are discontinued. Despite these concerns, the soaring demand for Ozempic has caused shortages in many hospitals and drugstores across China since late last year, affecting patients with diabetes who depend on the medication.

Growing Market and Competing Manufacturers

The weight loss drug market in China is expected to experience significant growth in the coming years. A government report from late 2020 revealed that over 50% of adults in China were overweight, highlighting the potential market size. Total sales of diabetes drugs, including semaglutide, could reach 40 billion yuan ($5.6 billion), a more than 600% increase from the current market size, according to an estimate by Shanghai-based Tebon Securities, per CNN.

Both Western and Chinese drugmakers are eager to tap into this growing market. Novo Nordisk, the Danish pharmaceutical firm behind Ozempic, has applied to China’s drug regulator to expand the scope of semaglutide’s use, potentially targeting weight loss. Chinese firms, on the other hand, are accelerating the development of generic versions of semaglutide.

Novo Nordisk’s patents for semaglutide in China are expected to expire in 2026, which could pave the way for the entry of generic versions into the market. However, Huadong Medicine, a Hangzhou-based pharmaceutical firm, has challenged the validity of Novo Nordisk’s patents. In September 2022, China’s State Intellectual Property Office ruled all core patents for Ozempic to be invalid. Novo Nordisk has appealed the decision, and a legal battle is currently underway at the Beijing Intellectual Property Court. The outcome of this case will determine the potential availability of generic semaglutide by domestic manufacturers in the market.

Social Media Crackdown and Rising Prices

In an attempt to curb the hype surrounding Ozempic, Xiaohongshu reportedly implemented a crackdown and deleted over 5,000 posts that shared weight loss experiences with the drug. The platform accused many of these posts of exaggerating the drug’s effectiveness and cautioned users against blindly believing such content. However, such measures have not been sufficient to quell the frenzy. The pressure to conform to prevailing beauty standards, especially among women, has contributed to the persistent demand for Ozempic in China.

Bloomberg reported in May that the drug quickly had a shortage since many turned to fake prescriptions and scalpers just to secure doses. Several have acquired Ozempic through doctors for off-label use, while others purchased the drug on e-commerce platforms like Taobao and JD.com with other people’s prescriptions.

The rising demand drove up prices online, with scalpers taking advantage of desperate buyers. While the official cost of a 1.5 mg dose of Ozempic in public hospitals is 478 yuan ($67) according to China’s National Reimbursement Drugs List, the medication is currently priced 36% to 151% higher on platforms like Taobao.

Published by Medicaldaily.com



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Feeling Tired All The Time? Possible Causes And Solutions

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Long days of work, lack of sleep, and stress at the office can be the most common factors that make you feel tired. However, feeling “tired all the time” (TATT) without known reasons can be an indication of an underlying health issue that needs immediate attention.

Finding the exact cause of the lingering tiredness can be the first step toward solving the symptom.

Health conditions that cause fatigue:

1. Anemia – Anemia is one of the most common causes of fatigue. A person who has anemia does not have enough red blood cells in the body, causing symptoms such as tiredness, dizziness, feeling cold and crankiness.

Most often, anemia is caused by iron deficiency. Hence, the condition can be best resolved by including iron-rich foods in the diet and use of iron supplements.

2. Sleep Apnea – It causes the body to stop breathing momentarily during sleep. The condition can affect the quality of sleep and hence make you feel fatigued.

For milder cases of sleep apnea, lifestyle changes such as losing weight or quitting smoking can help solve the sleep disorder. In more severe cases where there is an obstruction in breathing, surgeries and therapies can help.

3. Diabetes – A person who has diabetes has changes in blood sugar level, which can cause fatigue. A patient who is already on diabetic medication can also experience tiredness as a side effect of the medication.

Early identification and taking the correct treatment is the key to managing diabetes. Losing extra weight and having a healthy diet also help in the treatment.

4. Thyroid – Thyroid diseases can be due to an overactive or an underactive thyroid gland. In people who have an underactive thyroid (hypothyroidism), the metabolism slows down leading to symptoms such as lethargy and fatigue. In people with an overactive thyroid (hyperthyroidism), the metabolism speeds up leading to fatigue and difficulty sleeping.

Right diet and lifestyle choices, along with medications, can help in thyroid management.

5. Infections – A person can show symptoms of fatigue when the body is fighting a viral or bacterial infection. Infections ranging from the flu to HIV can cause tiredness.

Along with fatigue, other symptoms such as fever, headache, body aches, shortness of breath and appetite loss can also accompany the infection. Treating the symptoms and taking adequate rest helps in faster recovery.

6. Food allergies – Fatigue may be an early warning sign of hidden food allergies and autoimmune disorders such as celiac disease. Identifying the allergen using a food allergy test or through an elimination diet can help in allergy treatment.

7. Heart disease – If you feel exhausted from an activity that used to be easy, then it is good to check your heart health, as fatigue can be an indication of underlying heart disease.

8. Depression/ anxiety – Fatigue can also be an indicator of a mental health disorder such as depression or anxiety. A combination of medication and psychotherapy can help relieve symptoms.

Lifestyle causes

Apart from serious health conditions, certain lifestyle habits such as dehydration, poor diet, stress and insufficient sleep can cause exhaustion. Having a well-balanced diet, regular exercise and routine sleep can help solve fatigue caused by lifestyle habits.

Published by Medicaldaily.com



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How To Overcome Your Sleep Debt And Reclaim Energy

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Picture this: you’re burning the midnight oil, studying or binge-watching your favorite shows, all at the expense of a good night’s sleep. Have you ever stopped to think about the toll it takes on your body and mind? The consequences can be more serious than you might realize.

Not getting enough sleep can translate into a multitude of issues, including weight gain, lack of focus, tiredness, a haze of confusion, and even depression. If you too are encountering similar issues lately then chances are you have a sleep debt.

Wondering what is sleep debt?

People from 13-18 years of age need 8 hours of sleep, whilst adults beyond that age will require at least 7 hours of snooze.

Sleep debt is a collection of the total hours you haven’t slept or traded your sleep for something else. Sleep debt keeps piling up as a person falls short of the total hours of sleep recommended for an adult, according to the Centers for Disease Control and Prevention.

And when you keep letting go of your sleep for other activities, the body adapts to the new normal and effects start to reflect on the energy levels, which deplete.

“However, like every other debt out there, this too has a repayment option,” Dr. Kunal Kumar, medical director of the Sleep Center at Einstein Medical Center in Philadelphia, told Livestrong.

Below are some expert-vetted ways you can pay back the sleep debt. (Courtesy: Livestrong and Sleepfoundation)

Just like financial debt, imagine sleep debt as a debt you owe to your body. It needs to be repaid. The good news is that catching up on sleep is indeed possible.

  • Maintain a set sleep schedule: Overhauling the sleep schedule is a pretty difficult task to achieve, and it’s best to do that gradually. Create a set sleep schedule by making some small changes to your routine. Instead of making abrupt shifts in your bedtime or wake-up time, adjust them gradually by 15 to 30-minute increments.
  • Minimize your gadget usage: Wind down activities and minimize electronic usage before bed to promote better sleep. Relax and prepare for quality sleep by dimming the lights and setting an alarm for 30 minutes to an hour before bed.
  • Reshuffle your sleeping arrangements: Are you finding it hard to get a good night’s sleep due to excessive sweating? Well, here’s a handy solution: consider upgrading to a cooling mattress or opting for cooling sheets. These innovative sleep essentials can help regulate your body temperature, and keep you comfortably cool throughout the night, ensuring a more blissful slumber. Memory foam pillows can work wonders in relieving neck and back discomfort in case you are struggling with backache.
  • Improve the bedroom environment: Create a sleep-friendly bedroom environment by adjusting the temperature for comfort, and blocking out disruptive lights, or noises that might disturb your restful slumber. And if your mattress, pillow, or sheets are worn out or no longer providing the support you need, consider treating yourself to new ones.

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Omega-3 Fatty Acids Slow The Progression Of Amyotrophic Lateral Sclerosis: Study

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Omega-3 fatty acids are known for a range of health benefits, from promoting brain and heart health to reducing inflammation and protection against several chronic conditions.

In a new study, researchers found that omega-3 acids, especially the type found in foods like flaxseeds, walnuts, chia seeds, canola oil and soybean oil, can slow down the progression of amyotrophic lateral sclerosis (ALS).

It is a debilitating nervous system disease that gradually worsens over time and can be fatal. The condition results in a loss of muscle control and affects the nerve cells in the brain and spinal cord. It is also known as Lou Gehrig’s disease after the baseball player who was diagnosed with it.

The initial symptoms of the disease include muscle weakness, difficulty in walking and hand movements. The symptoms can slowly progress to difficulties with chewing, swallowing, speaking and breathing.

The exact cause of ALS is not known. However, around 10% of people get it from a risk gene passed down from a family member. It is estimated that more than 32,000 people in the U.S. live with the condition.

In the latest study, researchers from Harvard T.H. Chan School of Public Health in Massachusetts evaluated 449 people living with ALS in a clinical trial. The team assessed the severity of their symptoms, the progression of their disease, along with the levels of omega-3 fatty acids in their blood, for 18 months.

The study suggested that alpha-linolenic acid (ALA), a type of omega-3 found in plants, is particularly beneficial in slowing the progression of ALS. The participants with the highest levels of ALA had a 50% reduced risk of death during the study period compared to those with the lowest levels of ALA.

Researchers also found a reduction in death risk in participants who had eicosapentaenoic acid, the type of omega-3 fatty acid found in fatty fish and fish oil, and linoleic acid found in vegetable oils, nuts and seeds.

A previous study conducted by the same team suggested that a diet high in ALA and higher blood levels of the nutrient could reduce the risk of developing the condition.

“In this study, we found that among people living with ALS, higher blood levels of ALA were also associated with a slower disease progression and a lower risk of death within the study period. These findings, along with our previous research suggest that this fatty acid may have neuroprotective effects that could benefit people with ALS,” said Kjetil Bjornevik, the lead author of the study.

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